Diane Wagner
Assistant Professor
Education: Ph.D. - University of California at Berkeley
Research Interests: Soft tissue mechanics, bioengineering, tissue engineering, mechanobiology
Courses: Solid Mechanics; Tissue Engineering; Cell Mechanics
Email: dwagner@nd.edu
Phone: 574.631.5735
Office: 145 Multidisciplinary Research Building
Website: www.nd.edu/~dwagner
Dr. Wagner directs the Soft Tissue Research Laboratory (STRLab) in the Multidisciplinary Research Building. Her research focuses in two main areas: bone and cartilage tissue engineering using adult stem cells, and soft tissue mechanics and damage behavior. These projects leverage principles of engineering and the life sciences to better understand degeneration processes and to develop new techniques to repair damaged tissue. Dr. Wagner's research is multidisciplinary and includes undergraduate and graduate students and postdoctoral researchers from bioengineering, mechanical engineering and biology programs.
Selected Publications
- Wagner D.R., Lindsey D.P., Li K.W., Tummala P., Chandran S.E., Smith R.L., Longaker M.T., Carter D.R., Beaupre G.S. Hydrostatic pressure enhances chondrogenic differentiation of human bone marrow stromal cells in osteochondrogenic medium. Annals of Biomedical Engineering 2008 36(5) 813-20.
- Li K.W., Lindsey D.P., Wagner D.R., Giori N.J., Schurman D.J., Goodman S.B., Smith R.L., Carter D.R., Beaupre G.S. Gene regulation ex vivo within a wrap-around tendon. Tissue Engineering 2006 12(9) 2611-8.
- Xu Y., Malladi P., Wagner D.R. and Longaker M.T. Adipose-derived mesenchymal cells as a potential cell source for skeletal regeneration. Current Opinion in Molecular Therapeutics 2005 7(4) 300-305.
- Wagner D.R., Reiser K.M. and Lotz J.C. Glycation increases human annulus fibrosus stiffness in both experimental measurements and theoretical predictions. Journal of Biomechanics 2006 39(6) 1021-9.
- Hsieh A.H., Wagner D.R., Cheng, L.Y., and Lotz J.C. Dependence of Mechanical Behavior of the Murine Tail Disc on Regional Material Properties: A parametric Finite Element Study. Journal of Biomechanical Engineering 2005 127(7) 1158-1167.
- Wagner D.R. and Lotz J.C. Theoretical model and experimental results for the nonlinear elastic behavior of human annulus fibrosus. Journal of Orthopaedic Research 2004 22:901-9.
Research
Graduate Students
- Nathaniel Hollingsworth
- Megan McGann
- Andrew Steward
- Ali Vahdati
- Holly Weiss
