Contrast Agents for Micro-Computed Tomography of Microdamage in Bone
The objectives of this project are to 1) develop damage-specific contrast agents, with greater x-ray attenuation than bone, for micro-computed tomography (micro-CT) of microdamage; 2) evaluate the x-ray attenuation, deliverability and specificity of contrast agent formulations; and, 3) quantify the effects of the contrast agent on micro-CT images in damaged and undamaged bone, and correlate the measurements to conventional measures of microdamage.
Structural and Mechanical Anisotropy in Human Cortical Bone Tissue
The objectives of this work are to 1) characterize and quantitatively correlate anatomic variation in the mechanical anisotropy of human cortical bone with measurements of relevant structural features, 2) use this data to develop new micromechanical models which account for non-uniformity and anisotropy prior to hierarchical scaling, and 3) apply the knowledge gained in the design and synthesis of new orthopaedic biomaterials which can be tailored to function as a mechanical analog to human cortical bone.
Welcome to the Ryan K. Roeder
Welcome to the website for Professor Ryan K. Roeder and the Roeder Research Lab.