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PhD Candidate Chistopher M. Jasinski - "Experimental Fluid Mechanic Evaluation of Liner Drag and Acoustic-Drag Interaction"
The purpose of this dissertation is to establish the current state of the art in acoustic liner drag research, describe recently designed and built facilities at the University of Notre Dame for conducting such research, discuss the coupling of aerodynamic drag and acoustic excitation with liners, and offer conclusions and recommendations for future work in the area.
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PhD Candidate Anne Legault Tufts - "Numerical Investigation of Airfoil-Turbulence Interaction Noise in Low Mach Number Flows"
The sound generated by marine propellers and hydrofoils interacting with incoming turbulent flow is a complex problem that has been studied for many decades. Early works exploring airfoil interactions with turbulent structures involved only simplified flow fields. Models were produced to predict radiated sound, but were limited in use due to assumptions that could be violated in realistic flow applications. More recently, the e↵ects of airfoil thickness and angle of attack on sound radiation have been investigated, but the incoming flow was often limited to grid-generated turbulence.
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PhD Candidate Zhi Wang - "Spatial Systems Modeling and Control of a Microscale Additive Manufacturing Process"
Microscale additive manufacturing (µ-AM) processes are a class of manufacturing processes used to fabricate micron-sized structures in a sequence of direct additions of materials as instructed by a digital file, as opposed to the lithographic patterning and subtractive etching used in traditional microscale manufacturing.
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BioPhD Candidate Matthew Meagher - "Engineering Synthetic Bone Graft Substitutes with Improved Mechanical Properties, Enhanced Bioactivity, and On-Demand Growth Factor Delivery"
An unmet clinical need exists for synthetic bone graft substitutes which can perform comparably to autograft in the repair of bone defects. Therefore, the overall objective of this dissertation was to investigate the design of HA-collagen scaffolds to provide chemotactic and mechanical signals which direct angiogenesis and osteogenesis during bone regeneration.
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PhD Candidate Christopher L. Kelley - "Airfoil Leading and Trailing Edge Separation Control Using SDBD Plasma Actuators"
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PhD Candidate Liuxian Zhao - "Structural Tailoring for Tomographic Damage Detection, Vibration Control, and Energy Harvesting"
This research explores the use of structural tailoring techniques to achieve multiple functionalities, such as, structural damage detection, vibration control, and energy harvesting in thin-walled metallic structures. From a general perspective, structural tailoring techniques provide a viable approach to induce vibration localization, which is an element to enable the above functionalities.
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PhD Candidate Michael J. Johnson - "Non-centrosymmetric Materials for the Generation of Atmospheric Pressure Gas Discharges"
Atmospheric air plasmas are driven through large electric fields (>3 kV/mm) generated between one or more electrodes. The input voltage required to produce this electric field and to sustain a plasma in atmospheric air is often prohibitive for a number of different applications due to size, safety and cost constraints of the required power supply. To reduce the required input voltage, this works investigates inherent characteristics of certain polar non-centrosymmetric crystals to determine if they can be beneficial for discharge formation.
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PhD Candidate Andrew S. Gillman - "Predicting Effective Material Properties of Heterogeneous Composites from Well-resolved Higher Order Statistical Description of Morphology"
Heterogeneous systems are present in a variety of scientific and engineering fields including biology, structural engineering, aerospace systems, material science, and geology, just to name a few. Many of these materials arrange randomly with locally complex features and only lend themselves to being characterized statistically. Of particular interest to this work is determining effective (macroscopic) transport and mechanical properties of particulate composites from higher order statistical data, which is a fundamental problem studied by many including Einstein and Maxwell. The geometrical arrangement of heterogeneous materials plays a critical role in a material’s behavior, and this work illustrates that the detailed characterization of real materials is essential to accurately predict the macroscopic (overall/effective) behavior.
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BioPhD Candidate Nur Mustafaoglu - "Design of Antibody-Based Diagnostics and affinity Chromatography Systems Utilizing the Nucleotide Binding Site (NBS)"
This dissertation focuses on developing advanced diagnostic systems, efficient antibody purification techniques, and novel antibody-drug conjugation methods while aiming to improve availability of antibody-based technologies to end-users. Antibodies have become widely used agents for clinical treatment of cancers and autoimmune diseases due to their high level of specificity and selectivity toward known target molecules (antigens) found to be overexpressed on cancerous cells. Despite the many techniques that utilize antibodies necessitate that they are modified in some way by conjugating functional ligands to them – endowing them with specific functionalities unique for each intended application – they are still in need of improvement.
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PhD Candidate Lionel O. Pittman - "Aerothermal Experiments in Turbine Rim Seals"
Purge flows are necessary for ensuring that hot gasses do not penetrate the thermally sensitive rim seal and disk cavity regions of turbines. The temperature and mass flow rate of the purge air can affect the component life and aerodynamic performance of a turbine stage. Therefore it is of interest to understand the basic mechanisms that govern this complex flow problem.
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