Tag: research

A pipette places drops of green liquid onto a microscope slide containing a small device

Heart-on-a-chip device identifies youth-enhancing “cocktail” to repair old hearts

The heart is a pump that wears out over time—that, at least, was the prevailing view. New research has shown that the heart’s aging results from changes in intercellular communications, which tell heart cells, sometimes even healthy ones, to stiffen and break down. By decoding these complex …

Katharine White and Donny Hanjaya-Putra

Notre Dame researchers uncover the molecular driving force behind hallmark of aggressive, metastatic cancers

To invade healthy tissues and continue growing, aggressive cancers mimic and circumvent the body’s native piping system of veins and arteries. Through this process, known as vasculogenic mimicry (VM), tumor cells form fluid-conducting channels that transport blood, oxygen, and nutrients directly …

A young woman looks at a microscope slide that has a dab of clear gel in the middle of it

3D-bioprinted model offers new way to study and treat obesity-related heart disease

Heart disease is the leading cause of death among people with obesity, a condition affecting one in eight people worldwide. Studies show that fat around the heart can fuel inflammation, damage heart muscle cells, disrupt heart rhythm and increase the risk of heart failure, but the precise …

John Fisher

Leading biomedical engineer John Fisher to direct Notre Dame’s Bioengineering & Life Sciences Initiative

Internationally recognized biomedical engineer John Fisher will join the University of Notre Dame as director of the campus-wide Bioengineering & Life Sciences Initiative (BELS) and Arthur J. Schmitt Professor in the Department of Aerospace and Mechanical Engineering. His appointment begins …

Meenal Datta, Yichun Wang, and Donny Hanjaya-Putra

Notre Dame Engineering faculty earn three consecutive CMBE Rising Star Awards (2024–26)

For three years in a row, a faculty member from the University of Notre Dame’s College of Engineering has won the prestigious CMBE Rising Star Award given by the Biomedical Engineering Society’s (BMES) Cellular and Molecular Bioengineering Special Interest Group (CMBE-SIG). CMBE-SIG …

Two researchers in white lab coats and safety glasses work in a lab. A man in blue gloves uses a tool to transfer liquid into a small container near a multi-well plate with reddish liquid. A woman observes him, smiling softly.

Physical pressure on the brain triggers neurons’ self-destruction programming

To think, feel, talk and move, neurons send messages through electrical signals in the brain and spinal cord. This intricate communication network is built of billions of neurons connected by synapses and managed and modified by glial cells. When neurons die, this communication network is …

Three men work on scientific equipment in a lab. A man in a blue plaid shirt holds a black conical object, while another with a beard inserts a black tube into a large silver metallic apparatus. A man in a blue polo observes the process.

Alumni founder of carbon-capture start-up receives NSF funding to collaborate with Notre Dame researchers

Alec Houpt, who earned his doctorate from the Department of Aerospace and Mechanical Engineering (AME) at the University of Notre Dame in 2020, will collaborate with Sergey Leonov, research professor in AME, to pursue the development of a supersonic nozzle designed to freeze and …

A blue glove holds a petri dish while a pipette places pink drops of liquid

Fighting to cure brain cancer

To better understand glioblastoma, an aggressive brain cancer, Meenal Datta, the Jane Schoelch DeFlorio Collegiate Professor of Aerospace and Mechanical Engineering, thought outside the box—and off planet Earth. Read the …

Two blue, gloved hands hold the superblack material

Robust, low-cost superblack material leverages fundamental geometry and engineering methods

Cave entrances often appear black and forbidding.  Light enters, but little escapes, absorbed as it “bounces around” the interior. To trap light in much the same way, engineers at the University of Notre Dame have devised a superblack material from a matrix of microscopic, …

The Golden Dome against a blue sky

Notre Dame opens applications for 2026 Provost’s Postdoctoral Fellowship program

The University of Notre Dame is accepting applications for the next cohort of Provost’s Postdoctoral Fellows, a select group of early-career scholars in science, engineering, and the liberal arts who are committed to Notre Dame’s mission to be a powerful force for good in the world. Up to …